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Patients must have histologically proven classical Hodgkin lymphoma excluding Nodular lymphocyte predominant Hodgkin lymphoma.
Patients must have a mediastinal mass > 0.33 maximum intrathoracic diameter on standing postero-anterior chest X-ray or measuring > 10 cm in its largest diameter on axial CT images, to be completed within 28 days prior to registration. Patients must have no prior treatment (chemotherapy or radiation therapy) for Hodgkin lymphoma.
The purpose of this study is to test the usefulness of PET/CT scans during treatment in selecting the best combination of chemotherapy drugs/treatment for treating patients who have Hodgkin lymphoma