CONTACT INFORMATION http://www.loyola.org
Aleksey Zima
Ph.D.
  • Assistant Professor
  • Cell and Molecular Physiology
Research Keywords
  • Calcium Signaling
  • Heart
Publications

The Role of Dyadic Organization in Regulation of Sarcoplasmic Reticulum Ca(2+) Handling during Rest in Rabbit Ventricular MyocytesBovo,E.; de Tombe,P. P.; Zima,A. V.Biophysical journal 2014 ;106(9):1902-1909

Ca handling during excitation-contraction coupling in heart failureZima,A. V.; Bovo,E.; Mazurek,S. R.; Rochira,J. A.; Li,W.; Terentyev,D.Pflugers Archiv : European journal of physiology 2014 ; ( ):

Effects of mitochondrial uncoupling on Ca(2+) signaling during excitation-contraction coupling in atrial myocytesZima,A. V.; Pabbidi,M. R.; Lipsius,S. L.; Blatter,L. A.American journal of physiology.Heart and circulatory physiology 2013 ;304(7):H983-93

Mechanisms of Ca(2)+ handling in zebrafish ventricular myocytesBovo,E.; Dvornikov,A. V.; Mazurek,S. R.; de Tombe,P. P.; Zima,A. V.Pflugers Archiv : European journal of physiology 2013 ;465(12):1775-1784

Regulation of sarcoplasmic reticulum Ca release by cytosolic glutathione in rabbit ventricular myocytesMazurek,S. R.; Bovo,E.; Zima,A. V.Free radical biology & medicine 2013 ; ( ):

Reactive oxygen species contribute to the development of arrhythmogenic Ca2 waves during -adrenergic receptor stimulation in rabbit cardiomyocytes.Bovo,E.; Lipsius,S. L.; Zima,A. V.Journal of Physiology 2012 ;590(Pt 14):3291-3304

Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes.Sarkey,J. P.; Chu,M.; McShane,M.; Bovo,E.; Mou,Y. A.; Zima,A. V.; de Tombe,P. P.; Kartje,G. L.; Martin,J. L.Journal of Molecular & Cellular Cardiology 2011 ;50(6):1044-1055

Phospholamban binds with differential affinity to calcium pump conformers.Bidwell,P.; Blackwell,D. J.; Hou,Z.; Zima,A. V.; Robia,S. L.Journal of Biological Chemistry 2011 ;286(40):35044-35050

Partial inhibition of sarcoplasmic reticulum ca release evokes long-lasting ca release events in ventricular myocytes: role of luminal ca in termination of ca release.Zima,A. V.; Picht,E.; Bers,D. M.; Blatter,L. A.Biophysical journal 2008 ;94(5):1867-1879

Ginsenoside Re suppresses electromechanical alternans in cat and human cardiomyocytes.Wang,Y. G.; Zima,A. V.; Ji,X.; Pabbidi,R.; Blatter,L. A.; Lipsius,S. L.American Journal of Physiology - Heart & Circulatory Physiology 2008 ;295(2):H851-9

IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytesDomeier,T. L.; Zima,A. V.; Maxwell,J. T.; Huke,S.; Mignery,G. A.; Blatter,L. A.American Journal of Physiology - Heart & Circulatory Physiology 2008 ;294(2):H596-604

Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells.Aromolaran,A. S.; Zima,A. V.; Blatter,L. A.American Journal of Physiology - Cell Physiology 2007 ;293(1):106-118

IP3-dependent nuclear Ca2+ signalling in the mammalian heart.Zima,A. V.; Bare,D. J.; Mignery,G. A.; Blatter,L. A.Journal of Physiology 2007 ;584(Pt 2):601-611

SparkMaster: automated calcium spark analysis with ImageJ.Picht,E.; Zima,A. V.; Blatter,L. A.; Bers,D. M.American Journal of Physiology - Cell Physiology 2007 ;293(3):1073-1081

Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution.Remus,T. P.; Zima,A. V.; Bossuyt,J.; Bare,D. J.; Martin,J. L.; Blatter,L. A.; Bers,D. M.; Mignery,G. A.Journal of Biological Chemistry 2006 ;281(1):608-616

Regional differences in spontaneous Ca2+ spark activity and regulation in cat atrial myocytes.Sheehan,K. A.; Zima,A. V.; Blatter,L. A.Journal of Physiology 2006 ;572(Pt 3):799-809

Palytoxin disrupts cardiac excitation-contraction coupling through interactions with P-type ion pumps.Kockskamper,J.; Ahmmed,G. U.; Zima,A. V.; Sheehan,K. A.; Glitsch,H. G.; Blatter,L. A.American Journal of Physiology - Cell Physiology 2004 ;287(2):527-538

Inositol-1,4,5-trisphosphate-dependent Ca(2+) signalling in cat atrial excitation-contraction coupling and arrhythmias.Zima,A. V.; Blatter,L. A.Journal of Physiology 2004 ;555(Pt 3):607-615

Effects of cytosolic NADH/NAD(+) levels on sarcoplasmic reticulum Ca(2+) release in permeabilized rat ventricular myocytes.Zima,A. V.; Copello,J. A.; Blatter,L. A.Journal of Physiology 2004 ;555(Pt 3):727-741

Differential modulation of cardiac and skeletal muscle ryanodine receptors by NADH.Zima,A. V.; Copello,J. A.; Blatter,L. A.FEBS letters 2003 ;547(1-3):32-36

Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.Zima,A. V.; Kockskamper,J.; Mejia-Alvarez,R.; Blatter,L. A.Journal of Physiology 2003 ;550(Pt 3):765-783

Education
Fellowship
  • University of Florida, Electrophysiology
Languages
  • Ukrainian
  • Russian
Interests
  • History