Basabi Rana
  • Associate Professor
  • Gastroenterology
  • Cell and Molecular Physiology

Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.Rangasamy,V.; Mishra,R.; Sondarva,G.; Das,S.; Lee,T. H.; Bakowska,J. C.; Tzivion,G.; Malter,J. S.; Rana,B.; Lu,K. P.; Kanthasamy,A.; Rana,A.Proceedings of the National Academy of Sciences of the United States of America 2012 ;109(21):8149-8154

Mixed lineage kinase 3 modulates beta-catenin signaling in cancer cellsThylur,R. P.; Senthivinayagam,S.; Campbell,E. M.; Rangasamy,V.; Thorenoor,N.; Sondarva,G.; Mehrotra,S.; Mishra,P.; Zook,E.; Le,P. T.; Rana,A.; Rana,B.The Journal of biological chemistry 2011 ;286(43):37470-37482

Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertensionZhang,K.; Rao,F.; Wang,L.; Rana,B. K.; Ghosh,S.; Mahata,M.; Salem,R. M.; Rodriguez-Flores,J. L.; Fung,M. M.; Waalen,J.; Tayo,B.; Taupenot,L.; Mahata,S. K.; O'Connor,D. T.Journal of the American College of Cardiology 2010 ;55(14):1463-1475

TRAF2-MLK3 interaction is essential for TNF-alpha-induced MLK3 activation.Sondarva,G.; Kundu,C. N.; Mehrotra,S.; Mishra,R.; Rangasamy,V.; Sathyanarayana,P.; Ray,R. S.; Rana,B.; Rana,A.Cell research 2010 ;20(1):89-98

Estrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells.Rangasamy,V.; Mishra,R.; Mehrotra,S.; Sondarva,G.; Ray,R. S.; Rao,A.; Chatterjee,M.; Rana,B.; Rana,A.Cancer research 2010 ;70(4):1731-1740

Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.Mishra,P.; Senthivinayagam,S.; Rangasamy,V.; Sondarva,G.; Rana,B.Molecular Endocrinology 2010 ;24(3):598-607

Caspase-mediated cleavage of beta-catenin precedes drug-induced apoptosis in resistant cancer cells.Senthivinayagam,S.; Mishra,P.; Paramasivam,S. K.; Yallapragada,S.; Chatterjee,M.; Wong,L.; Rana,A.; Rana,B.Journal of Biological Chemistry 2009 ;284(20):13577-13588

Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.Mishra,R.; Barthwal,M. K.; Sondarva,G.; Rana,B.; Wong,L.; Chatterjee,M.; Woodgett,J. R.; Rana,A.Journal of Biological Chemistry 2007 ;282(42):30393-30405

Protective role of fish oil (Maxepa) on early events of rat mammary carcinogenesis by modulation of DNA-protein crosslinks, cell proliferation and p53 expression.Manna,S.; Chakraborty,T.; Damodaran,S.; Samanta,K.; Rana,B.; Chatterjee,M.Cancer Cell International 2007 ;7( ):6

Molecular basis of vanadium-mediated inhibition of hepatocellular preneoplasia during experimental hepatocarcinogenesis in rats.Chakraborty,T.; Swamy,A. H.; Chatterjee,A.; Rana,B.; Shyamsundar,A.; Chatterjee,M.Journal of cellular biochemistry 2007 ;101(1):244-258

Suppression of early stages of neoplastic transformation in a two-stage chemical hepatocarcinogenesis model: supplementation of vanadium, a dietary micronutrient, limits cell proliferation and inhibits the formations of 8-hydroxy-2'-deoxyguanosines and DNA strand-breaks in the liver of sprague-dawley rats.Chakraborty,T.; Chatterjee,A.; Rana,A.; Rana,B.; Palanisamy,A.; Madhappan,R.; Chatterjee,M.Nutrition & Cancer 2007 ;59(2):228-247

Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats.Chakraborty,T.; Pandey,N.; Chatterjee,A.; Ghosh,B.; Rana,B.; Chatterjee,M.Mutation research 2006 ;609(2):117-128

Vanadium mediated apoptosis and cell cycle arrest in MCF7 cell line.Ray,R. S.; Rana,B.; Swami,B.; Venu,V.; Chatterjee,M.Chemico-biological interactions 2006 ;163(3):239-247

Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells.Pradeep,A.; Sharma,C.; Sathyanarayana,P.; Albanese,C.; Fleming,J. V.; Wang,T. C.; Wolfe,M. M.; Baker,K. M.; Pestell,R. G.; Rana,B.Oncogene 2004 ;23(20):3689-3699

Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway.Sharma,C.; Pradeep,A.; Wong,L.; Rana,A.; Rana,B.Journal of Biological Chemistry 2004 ;279(34):35583-35594

Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1.Song,D. H.; Rana,B.; Wolfe,J. R.; Crimmins,G.; Choi,C.; Albanese,C.; Wang,T. C.; Pestell,R. G.; Wolfe,M. M.American Journal of Physiology - Gastrointestinal & Liver Physiology 2003 ;285(1):G217-22

Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival.Barthwal,M. K.; Sathyanarayana,P.; Kundu,C. N.; Rana,B.; Pradeep,A.; Sharma,C.; Woodgett,J. R.; Rana,A.Journal of Biological Chemistry 2003 ;278(6):3897-3902

COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer.Yao,M.; Song,D. H.; Rana,B.; Wolfe,M. M.British journal of cancer 2002 ;87(5):574-579