Charles Hemenway
M.D.,Ph.D.
Ronald McDonald House Charities Endowed Professor in Pediatric Oncology
Director, M.D./Ph.D. Program
Division Director, Pediatric Hematology/Oncology
Pediatric Hematology/Oncology
CONTACT INFORMATION
Specialties
Cancer in Children and Adolescents, Bleeding Disorders in Children and Adolescents, Anemia in Children and Adolescents
Locations
Board Certifications
Pediatric Hematology-Oncology - Subspecialty Cert: AM Board of Pediatrics
Publications
Hsp90 directly modulates the spatial distribution of AF9/MLLT3 and affects target gene expression.Lin,J. J.; Hemenway,C. S.Journal of Biological Chemistry 2010 ;285(16):11966-11973
Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenesChang,M. J.; Wu,H.; Achille,N. J.; Reisenauer,M. R.; Chou,C. W.; Zeleznik-Le,N. J.; Hemenway,C. S.; Zhang,W.Cancer research 2010 ;70(24):10234-10242
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.Bennett,C. A.; Winters,A. C.; Barretto,N. N.; Hemenway,C. S.Leukemia research 2009 ;33(7):937-947
The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells.Palermo,C. M.; Bennett,C. A.; Winters,A. C.; Hemenway,C. S.Leukemia research 2008 ;32(4):633-642
Hurricane Katrina's impact on pediatric and adult patients with sickle cell disease.Karras,N. A.; Hemenway,C. S.Journal of Health Care for the Poor & Underserved 2007 ;18(2):382-393
Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner.Zhang,W.; Xia,X.; Reisenauer,M. R.; Hemenway,C. S.; Kone,B. C.Journal of Biological Chemistry 2006 ;281(26):18059-18068
Education
Medical School
University of Massachusetts Medical School
Residency
University of Florida, Internal Medicine & Pediatrics
Fellowship
Duke University Medical Center, Pediatrics: Pediatric Hematology-Oncology
Languages
French
Interests & Hobbies
Dogs
Hiking
Fishing
Skiing