CONTACT INFORMATION http://www.loyola.org
Karen Griffin
M.D., FACP
  • Professor
  • Fellowship Program Director, Nephrology
  • Medical Director, LUHS Comprehensive Hypertension Program
  • Nephrology
Specialties
Chronic Kidney Disease, High Blood Pressure, Kidney Transplant, Systemic Lupus Erythematosus, Polycystic Kidney Disease, Kidney Stones, Diabetic Kidney Disease
Board Certifications
  • Internal Medicine - General Cert: AM Board of Internal Medicine
  • Nephrology - Subspecialty Cert: AM Board of Internal Medicine
Publications

Critical Blood Pressure Threshold Dependence of Hypertensive Injury and Repair in a Malignant Nephrosclerosis ModelGriffin,K. A.; Polichnowski,A.; Litbarg,N.; Picken,M.; Venkatachalam,M. A.; Bidani,A. K.Hypertension 2014 ; ( ):

Severe Renal Mass Reduction Impairs Recovery and Promotes Fibrosis after AKIPolichnowski,A. J.; Lan,R.; Geng,H.; Griffin,K. A.; Venkatachalam,M. A.; Bidani,A. K.Journal of the American Society of Nephrology : JASN 2014 ; ( ):

Blood pressure - renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused ratsPolichnowski,A. J.; Griffin,K. A.; Long,J.; Williamson,G. A.; Bidani,A. K.American journal of physiology.Renal physiology 2013 ; ( ):

Renal microvascular dysfunction, hypertension and CKD progressionBidani,A. K.; Polichnowski,A. J.; Loutzenhiser,R.; Griffin,K. A.CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 2013 ;22(1):1-9

Large BP-dependent and -independent differences in susceptibility to nephropathy after nitric oxide inhibition in Sprague-Dawley rats from two major suppliers.Griffin,K.; Polichnowski,A.; Licea-Vargas,H.; Picken,M.; Long,J.; Williamson,G.; Bidani,A.American Journal of Physiology - Renal Physiology 2012 ;302(1):F173-82

Large Bp-Dependent and -Independent Differences in Susceptibility to Nephropathy After Nitric Oxide Inhibition in Sprague-Dawley Rats from Two Major SuppliersGriffin,K. A.; Polichnowski,A. J.; Licea-Vargas,H.; Picken,M.; Long,J.; Williamson,G. A.; Bidani,A. K.American journal of physiology.Renal physiology 2011 ; ( ):

Solute and water excretion patterns in patients with nocturnal polyuriaHerek,J. I.; FitzGerald,M. P.; Mohindra,M.; Wickman,C.; Leehey,D. J.; Bidani,A. K.; Griffin,K. A.International Journal of Nephrology & Urology 2010 ;2(4):526-531

Angiotensin II type 2 receptor in chronic kidney disease: the good side of angiotensin II?.Griffin,K. A.; Bidani,A. K.Kidney international 2009 ;75(10):1006-1008

Protective importance of the myogenic response in the renal circulationBidani,A. K.; Griffin,K. A.; Williamson,G.; Wang,X.; Loutzenhiser,R.Hypertension 2009 ;54(2):393-398

Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension.Pravenec,M.; Churchill,P. C.; Churchill,M. C.; Viklicky,O.; Kazdova,L.; Aitman,T. J.; Petretto,E.; Hubner,N.; Wallace,C. A.; Zimdahl,H.; Zidek,V.; Landa,V.; Dunbar,J.; Bidani,A. K.; Griffin,K.; Qi,N.; Maxova,M.; Kren,V.; Mlejnek,P.; Wang,J.; Kurtz,T. W.Nature genetics 2008 ;40(8):952-954

Potential Risks of Calcium Channel Blockers in Chronic Kidney Disease.Griffin,K. A.; Bidani,A. K.Current Cardiology Reports 2008 ;10( ):448-455

Adverse renal consequences of obesityGriffin,K. A.; Kramer,H.; Bidani,A. K.American Journal of Physiology - Renal Physiology 2008 ;294(4):F685-96

Systolic and mean blood pressures and afferent arteriolar myogenic response dynamics: a modeling approach.Williamson,G. A.; Loutzenhiser,R.; Wang,X.; Griffin,K. A.; Bidani,A. K.American Journal of Physiology.Regulatory, Integrative and Comparative Physiology 2008 ;295(5):R1502-R1511

Dynamic blood pressure load and nephropathy in the ZSF1 (fa/fa cp) model of type 2 diabetes.Griffin,K. A.; Abu-Naser,M.; Abu-Amarah,I.; Picken,M. M.; Williamson,G. A.; Bidani,A. K.American Journal of Physiology - Renal Physiology 2007 ;293(5):F1605-13

Spontaneously reduced blood pressure load in the rat streptozotocin-induced diabetes model: potential pathogenetic relevance.Bidani,A. K.; Picken,M. M.; Hacioglu,R.; Williamson,G.; Griffin,K. A.American Journal of Physiology - Renal Physiology 2007 ;292(2):F647-54

The benefits of renin-angiotensin blockade in hypertension are dependent on blood-pressure lowering.Bidani,A. K.; Griffin,K. A.Nature Clinical Practice Nephrology 2006 ;2(10):542-543

Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanismsLoutzenhiser,R.; Griffin,K.; Williamson,G.; Bidani,A. K.American Journal of Physiology - Regulatory Integrative & Comparative Physiology 2006 ;290(5):R1153-67

Systolic blood pressure as the trigger for the renal myogenic response: protective or autoregulatory?Loutzenhiser,R.; Griffin,K. A.; Bidani,A. K.Current Opinion in Nephrology & Hypertension 2006 ;15(1):41-49

Characterization of dynamics in renal autoregulation using volterra models.Hacioglu,R.; Williamson,G. A.; Abu-Amarah,I.; Griffin,K. A.; Bidani,A. K.IEEE Transactions on Biomedical Engineering 2006 ;53(11):2166-2176

Hypertension and kidney damage.Griffin,K. A.Journal of clinical hypertension 2006 ;8(3):209-214

Progression of renal disease: renoprotective specificity of renin-angiotensin system blockadeGriffin,K. A.; Bidani,A. K.Clinical Journal of The American Society of Nephrology: CJASN 2006 ;1(5):1054-1065

Differential effects of salt on renal hemodynamics and potential pressure transmission in stroke-prone and stroke-resistant spontaneously hypertensive rats.Abu-Amarah,I.; Bidani,A. K.; Hacioglu,R.; Williamson,G. A.; Griffin,K. A.American Journal of Physiology - Renal Physiology 2005 ;289(2):F305-13

Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education SubcommitteeKurtz,T. W.; Griffin,K. A.; Bidani,A. K.; Davisson,R. L.; Hall,J. E.Arteriosclerosis, Thrombosis & Vascular Biology 2005 ;25(3):478-479

Recommendations for blood pressure measurement in humans and experimental animals. Part 2: Blood pressure measurement in experimental animals: a statement for professionals from the subcommittee of professional and public education of the American Heart Association council on high blood pressure researchKurtz,T. W.; Griffin,K. A.; Bidani,A. K.; Davisson,R. L.; Hall,J. E.Hypertension 2005 ;45(2):299-310

Pathophysiology of hypertensive renal damage: implications for therapyBidani,A. K.; Griffin,K. A.Hypertension 2004 ;44(5):595-601

Hypertensive renal damage: insights from animal models and clinical relevanceGriffin,K. A.; Bidani,A. K.Current hypertension reports 2004 ;6(2):145-153

Effects of calcium channel blockers on "dynamic" and "steady-state step" renal autoregulation.Griffin,K. A.; Hacioglu,R.; Abu-Amarah,I.; Loutzenhiser,R.; Williamson,G. A.; Bidani,A. K.American Journal of Physiology - Renal Physiology 2004 ;286(6):F1136-43

Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat.Griffin,K. A.; Picken,M. M.; Bidani,A. K.Kidney international 2004 ;65(1):209-218

"Step" vs. "dynamic" autoregulation: implications for susceptibility to hypertensive injury.Bidani,A. K.; Hacioglu,R.; Abu-Amarah,I.; Williamson,G. A.; Loutzenhiser,R.; Griffin,K. A.American Journal of Physiology - Renal Physiology 2003 ;285(1):F113-20

Long-term blood-pressure monitoring in unrestrained animals.Griffin,K. A.; Abu-Amarah,I.; Bidani,A. K.Methods in Molecular Medicine 2003 ;86( ):329-340

Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependentGriffin,K. A.; Abu-Amarah,I.; Picken,M. M.; Bidani,A. K.Hypertension 2003 ;41(2):201-206

Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms.Griffin,K. A.; Picken,M. M.; Giobbie-Hurder,A.; Bidani,A. K.Kidney international 2003 ;63(2):607-616

Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat.Churchill,P. C.; Churchill,M. C.; Griffin,K. A.; Picken,M. M.; Webb,R. C.; Kurtz,T. W.; Bidani,A. K.Kidney international 2002 ;61(5):1794-1800

Long-term renal consequences of hypertension for normal and diseased kidneysBidani,A. K.; Griffin,K. A.Current Opinion in Nephrology & Hypertension 2002 ;11(1):73-80

Genetic susceptibility to renal injury in hypertensionBidani,A. K.; Griffin,K. A.; Churchill,P. C.; Churchill,M. C.; St Lezin,E.; Kurtz,T. W.Experimental nephrology 2001 ;9(6):360-365

Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR.Griffin,K. A.; Churchill,P. C.; Picken,M. M.; Webb,R. C.; Kurtz,T. W.; Bidani,A. K.American Journal of Hypertension 2001 ;14(4 Pt 1):311-320

Relative antihypertensive and glomeruloprotective efficacies of enalapril and candesartan cilexetil in the remnant kidney model.Griffin,K. A.; Picken,M. M.; Bakris,G.; Bidani,A. K.Journal of Renin-Angiotensin-Aldosterone System 2001 ;2(1):s191-s195

Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model.Griffin,K. A.; Picken,M. M.; Bakris,G. L.; Bidani,A. K.Hypertension 2001 ;37(5):1268-1272

Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat.Griffin,K. A.; Picken,M. M.; Churchill,M.; Churchill,P.; Bidani,A. K.Journal of the American Society of Nephrology 2000 ;11(3):497-506

Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablationBidani,A. K.; Griffin,K. A.; Bakris,G.; Picken,M. M.Kidney international 2000 ;57(4):1651-1661

Education
Medical School
  • Rush Medical College of Rush University
Residency
  • Rush-Presbyterian-St. Luke's Medical Center, Internal Medicine: General
Fellowship
  • Rush-Presbyterian-St. Luke's Medical Center, Internal Medicine: Nephrology
Interests
  • Bicycling
  • Exercise
  • Gardening
  • Fishing