Endometrial Biopsy | Medical Services | Loyola Medicine

Endometrial Biopsy

What Is Endometrial Biopsy?

In an endometrial biopsy, tissue is removed from the lining of the uterus (endometrium) in order to diagnose abnormalities in cells or variations in hormone levels. This procedure is performed to determine if you have a uterine infection, endometrial cancer or endometriosis. You should not have this procedure if you are pregnant as it can lead to miscarriage.

What to Expect with an Endometrial Biopsy

This procedure can be performed in around 10 minutes in your doctor’s office and usually does not require any anesthesia. Your doctor will insert a thin, flexible tube (pipelle) through the opening of your cervix to get a tissue sample from the lining of the uterus. 

Side Effects of Endometrial Biopsy

Side effects from an endometrial biopsy are mild and may include:

  • Light spotting or bleeding
  • Mild cramping

You will be advised to not use tampons or have sexual intercourse for several days after this procedure.

Risks of Endometrial Biopsy

Infection is a risk in any invasive procedure such as an endometrial biopsy. You should contact your doctor if you have any of the following symptoms:

  • Abnormal or foul-smelling vaginal discharge
  • Bleeding for more than two days after the procedure
  • Fever or chills
  • Heavy bleeding
  • Severe pain in the lower abdomen