Paul C. Kuo
  • John P. Igini, M.D., Professor of Surgery
  • Department Chairperson, Surgery
  • Director, Oncology Institute
  • Surgical Oncology
  • Molecular Pharmacology and Therapeutics
Liver Transplant, Bile Duct Cancer, Hernia, Gallbladder Disorders, Minimally Invasive Surgery, Liver Cancer, Liver Disorders, Bile Duct Disorders, Gastroesophageal Reflux (GERD), Gastrointestinal Surgery
Board Certifications
  • Clinical Informatics - Subspecialty: AM Board of Preventive Medicine
  • Surgery - General Cert: AM Board of Surgery
  • Surgical Critical Care - Subspecialty Cert: AM Board of Surgery

New Onset Postoperative Atrial Fibrillation Predicts Long-Term Cardiovascular Events Following Radical CystectomyBlackwell,R. H.; Ellimoottil,C.; Bajic,P.; Kothari,A.; Zapf,M.; Kliethermes,S.; Flanigan,R. C.; Quek,M. L.; Kuo,P. C.; Gupta,G. N.The Journal of urology 2015 ; ( ):

Renal response following perioperative ketorolac analgesia in living kidney donationLi,N. Y.; Tong,L.; Barbas,A. S.; Bhattacharya,S. D.; Wai,P. Y.; Kuo,P. C.Transplantation 2015 ;99(3):e22-3

Alcohol Inhibits Osteopontin Dependent Transforming Growth Factor-beta1 Expression in Human Mesenchymal Stem CellsDriver,J.; Weber,C. E.; Callaci,J. J.; Kothari,A. N.; Zapf,M. A.; Roper,P. M.; Borys,D.; Franzen,C. A.; Gupta,G. N.; Wai,P. Y.; Zhang,J.; Denning,M. F.; Kuo,P. C.; Mi,Z.The Journal of biological chemistry 2015 ; ( ):

FAK Mediates a Compensatory Survival Signal Parallel to PI3K-AKT in PTEN-Null T-ALL CellsYou,D.; Xin,J.; Volk,A.; Wei,W.; Schmidt,R.; Scurti,G.; Nand,S.; Breuer,E. K.; Kuo,P. C.; Breslin,P.; Kini,A. R.; Nishimura,M. I.; Zeleznik-Le,N. J.; Zhang,J.Cell reports 2015 ;10(12):2055-2068

Characterization of uptake and internalization of exosomes by bladder cancer cellsFranzen,C. A.; Simms,P. E.; Van Huis,A. F.; Foreman,K. E.; Kuo,P. C.; Gupta,G. N.BioMed research international 2014 ;2014( ):619829

Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in miceCoombes,J. D.; Swiderska-Syn,M.; Dolle,L.; Reid,D.; Eksteen,B.; Claridge,L.; Briones-Orta,M. A.; Shetty,S.; Oo,Y. H.; Riva,A.; Chokshi,S.; Papa,S.; Mi,Z.; Kuo,P. C.; Williams,R.; Canbay,A.; Adams,D. H.; Diehl,A. M.; van Grunsven,L. A.; Choi,S. S.; Syn,W. K.Gut 2014 ; ( ):

Engagement, workplace satisfaction, and retention of surgical specialists in academic medicine in the United StatesWai,P. Y.; Dandar,V.; Radosevich,D. M.; Brubaker,L.; Kuo,P. C.Journal of the American College of Surgeons 2014 ;219(1):31-42.e12

Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4a transcriptional activityGuo,H.; Gao,C.; Mi,Z.; Wai,P. Y.; Kuo,P. C.The Biochemical journal 2014 ;461(2):347

Osteopontin is up-regulated in chronic hepatitis C and is associated with cellular permissiveness for hepatitis C virus replicationChoi,S. S.; Claridge,L. C.; Jhaveri,R.; Swiderska-Syn,M.; Clark,P.; Suzuki,A.; Pereira,T. A.; Mi,Z.; Kuo,P. C.; Guy,C. D.; Pereira,F. E.; Diehl,A. M.; Patel,K.; Syn,W. K.Clinical science (London, England : 1979) 2014 ;126(12):845-855

Novel clinical therapeutics targeting the epithelial to mesenchymal transitionKothari,A. N.; Mi,Z.; Zapf,M.; Kuo,P. C.Clinical and translational medicine 2014 ;3( ):35-014-0035-0. eCollection 2014

Osteopontin mediates an MZF1-TGF-beta1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancerWeber,C. E.; Kothari,A. N.; Wai,P. Y.; Li,N. Y.; Driver,J.; Zapf,M. A.; Franzen,C. A.; Gupta,G. N.; Osipo,C.; Zlobin,A.; Syn,W. K.; Zhang,J.; Kuo,P. C.; Mi,Z.Oncogene 2014 ; ( ):

Doing well by doing good: linking access with qualityChang,V.; Kuo,P. C.; Wai,P. Y.American Journal of Surgery 2014 ; ( ):

Osteopontin Up-Regulates Critical Epithelial-Mesenchymal Transition Transcription Factors to Induce an Aggressive Breast Cancer PhenotypeLi,N. Y.; Weber,C. E.; Mi,Z.; Wai,P. Y.; Cuevas,B. D.; Kuo,P. C.Journal of the American College of Surgeons 2013 ; ( ):

An MAPK-dependent pathway induces epithelial-mesenchymal transition via Twist activation in human breast cancer cell linesLi,N. Y.; Weber,C. E.; Wai,P. Y.; Cuevas,B. D.; Zhang,J.; Kuo,P. C.; Mi,Z.Surgery 2013 ;154(2):404-410

Acute Graft Dysfunction After Living-related Renal TransplantEllimoottil,C.; Brandt,W.; Bernardi,K.; Evans,A.; Mehta,V.; Picken,M. M.; Phelan,K.; Heinrich,L.; Milner,J.; Wai,P. Y.; Asolati,M.; Kuo,P. C.; Lu,A. D.Urology 2013 ; ( ):

Obesity and trends in malpractice claims for physicians and surgeonsWeber,C. E.; Talbot,L. J.; Geller,J. M.; Kuo,M. C.; Wai,P. Y.; Kuo,P. C.Surgery 2013 ; ( ):

Neurodegeneration in Streptozotocin-Induced Diabetic Rats is Attenuated by Treatment with ResveratrolJing,Y. H.; Chen,K. H.; Kuo,P. C.; Pao,C. C.; Chen,J. K.Neuroendocrinology 2013 ; ( ):

Transcriptional regulators of the DeltaNp63: their role in limbal epithelial cell proliferationHsueh,Y. J.; Kuo,P. C.; Chen,J. K.Journal of cellular physiology 2013 ;228(3):536-546

Comparing 20 years of national general surgery malpractice claims data: obesity versus morbid obesityWeber,C. E.; Talbot,L. J.; Geller,J. M.; Kuo,M. C.; Wai,P. Y.; Kuo,P. C.American Journal of Surgery 2013 ;205(3):293-7; discussion 297

Emetine Dihydrochloride: A Novel Therapy for Bladder CancerForeman,K. E.; Jesse,J. N.,3rd; Kuo,P. C.; Gupta,G. N.The Journal of urology 2013 ; ( ):

Intersecting pathways in inflammation and cancer: Hepatocellular carcinoma as a paradigmWai,P. Y.; Kuo,P. C.World journal of clinical oncology 2012 ;3(2):15-23

Impact of business infrastructure on financial metrics in departments of surgery.Wai,P. Y.; O'Hern,T.; Andersen,D. O.; Kuo,M. C.; Weber,C. E.; Talbot,L. J.; Kuo,P. C.Surgery 2012 ;152(4):729-734

Biplanar flap reconstruction for pressure ulcers: experience in patients with immobility from chronic spinal cord injuriesMehta,A.; Baker,T. A.; Shoup,M.; Brownson,K.; Amde,S.; Doren,E.; Shah,S.; Kuo,P.; Angelats,J.American Journal of Surgery 2012 ;203(3):303-307

The tumor microenvironmentWeber,C. E.; Kuo,P. C.Surgical oncology 2012 ;21(3):172-177

Epithelial-mesenchymal transition, TGF-beta, and osteopontin in wound healing and tissue remodeling after injuryWeber,C. E.; Li,N. Y.; Wai,P. Y.; Kuo,P. C.Journal of Burn Care & Research 2012 ;33(3):311-318

The role of osteopontin and osteopontin aptamer (OPN-R3) in fibroblast activityHunter,C.; Bond,J.; Kuo,P. C.; Selim,M. A.; Levinson,H.The Journal of surgical research 2012 ;176(1):348-358

Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft modelBhattacharya,S. D.; Mi,Z.; Kim,V. M.; Guo,H.; Talbot,L. J.; Kuo,P. C.Annals of Surgery 2012 ;255(2):319-325

Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markersBhattacharya,S. D.; Mi,Z.; Talbot,L. J.; Guo,H.; Kuo,P. C.Surgery 2012 ;152(3):449-454

Laparoscopic Treatment of Epiphrenic Diverticula: Preoperative Evaluation and Surgical Technique. How I Do ItFisichella,P. M.; Pittman,M.; Kuo,P. C.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2011 ;15(10):1861-71

The protective role of laparoscopic antireflux surgery against aspiration of pepsin after lung transplantation.Fisichella,P. M.; Davis,C. S.; Lundberg,P. W.; Lowery,E.; Burnham,E. L.; Alex,C. G.; Ramirez,L.; Pelletiere,K.; Love,R. B.; Kuo,P. C.; Kovacs,E. J.Surgery 2011 ;150(4):598-606

Will the clinicians support the researchers and teachers? Results of a salary satisfaction survey of 947 academic surgeons.Scarborough,J. E.; Bennett,K. M.; Schroeder,R. A.; Swedish,T. B.; Jacobs,D. O.; Kuo,P. C.Annals of Surgery 2009 ;250(3):432-439

Streptococcus equi primary bacteremia in a hepatitis-C cirrhotic patient.Aggarwal,H.; Smith,A. D.; Kuo,P. C.; Vikraman,D. S.Transplantation 2009 ;87(5):783

Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancerMi,Z.; Guo,H.; Kuo,P. C.BMC research notes 2009 ;2( ):119-0500-2-119

RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells.Mi,Z.; Guo,H.; Russell,M. B.; Liu,Y.; Sullenger,B. A.; Kuo,P. C.Molecular Therapy: the Journal of the American Society of Gene Therapy 2009 ;17(1):153-161

EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells.Zhang,J.; Guo,H.; Mi,Z.; Gao,C.; Bhattacharya,S.; Li,J.; Kuo,P. C.Experimental cell research 2009 ;315(2):304-312

Workforce projections for hepato-pancreato-biliary surgery.Scarborough,J. E.; Pietrobon,R.; Bennett,K. M.; Clary,B. M.; Kuo,P. C.; Tyler,D. S.; Pappas,T. N.Journal of the American College of Surgeons 2008 ;206(4):678-684

Osteopontin: regulation in tumor metastasisWai,P. Y.; Kuo,P. C.Cancer & Metastasis Reviews 2008 ;27(1):103-118

Functional analysis of tumor metastasis: modeling colon cancerWai,P. Y.; Reddy,S. K.; Kuo,P. C.Oncology Reviews 2008 ;2(1):9-20

Regionalization of hepatic resections is associated with increasing disparities among some patient populations in use of high-volume providers.Scarborough,J. E.; Pietrobon,R.; Clary,B. M.; Marroquin,C. E.; Bennett,K. M.; Kuo,P. C.; Pappas,T. N.Journal of the American College of Surgeons 2008 ;207(6):831-838

Relationship between provider volume and outcomes for orthotopic liver transplantation.Scarborough,J. E.; Pietrobon,R.; Tuttle-Newhall,J. E.; Marroquin,C. E.; Collins,B. H.; Desai,D. M.; Kuo,P. C.; Pappas,T. N.Journal of Gastrointestinal Surgery 2008 ;12(9):1527-1533

Supply and demand for liver transplant surgery: are we training enough surgeons?.Scarborough,J. E.; Tuttle-Newhall,J. E.; Pietrobon,R.; Marroquin,C. E.; Collins,B. H.; Desai,D. M.; Kuo,P. C.; Pappas,T. N.HPB 2008 ;10(1):25-29

Pro: low central venous pressure during liver transplantation--not too lowSchroeder,R. A.; Kuo,P. C.Journal of Cardiothoracic & Vascular Anesthesia 2008 ;22(2):311-314

The activity of RhoA is correlated with lymph node metastasis in human colorectal cancer.Takami,Y.; Higashi,M.; Kumagai,S.; Kuo,P. C.; Kawana,H.; Koda,K.; Miyazaki,M.; Harigaya,K.Digestive Diseases & Sciences 2008 ;53(2):467-473

"Ghost" publications among applicants to a general surgery residency program.Kuo,P. C.; Schroeder,R. A.; Shah,A.; Shah,J.; Jacobs,D. O.; Pietrobon,R.Journal of the American College of Surgeons 2008 ;207(4):485-489

Influence of long chain polyunsaturated fatty acids and ornithine concentrations on complications after renal transplant.Alexander,J. W.; Goodman,H. R.; Succop,P.; Light,J. A.; Kuo,P. C.; Moser,A. B.; James,J. H.; Woodle,E. S.Experimental & Clinical Transplantation: Official Journal of the Middle East Society for Organ Transplantation 2008 ;6(2):118-126

RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer.Emani,S.; Zhang,J.; Guo,L.; Guo,H.; Kuo,P. C.Surgery 2008 ;143(6):803-812

Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene.Guo,H.; Mi,Z.; Kuo,P. C.Journal of Biological Chemistry 2008 ;283(37):25209-25217

Osteopontin mediates Stat1 degradation to inhibit iNOS transcription in a cecal ligation and puncture model of sepsis.Guo,H.; Wai,P. Y.; Mi,Z.; Gao,C.; Zhang,J.; Kuo,P. C.Surgery 2008 ;144(2):182-188

Characterization of the PC4 binding domain and its interactions with HNF4alpha.Guo,H.; Gao,C.; Mi,Z.; Zhang,J.; Kuo,P. C.Journal of Biochemistry 2007 ;141(5):635-640

Resection of noncolorectal nonneuroendocrine liver metastases: a comparative analysis.Reddy,S. K.; Barbas,A. S.; Marroquin,C. E.; Morse,M. A.; Kuo,P. C.; Clary,B. M.Journal of the American College of Surgeons 2007 ;204(3):372-382

Extended hepatic resection for gallbladder cancer.Reddy,S. K.; Marroquin,C. E.; Kuo,P. C.; Pappas,T. N.; Clary,B. M.American Journal of Surgery 2007 ;194(3):355-361

Renal function with cyclosporine C2 monitoring, enteric-coated mycophenolate sodium and basiliximab: a 12-month randomized trial in renal transplant recipients.Cibrik,D.; Meier-Kriesche,H. U.; Bresnahan,B.; Wu,Y. M.; Klintmalm,G.; Kew,C. E.; Kuo,P. C.; Whelchel,J.; Cohen,D.; Baliga,P.; Akalin,E.; Benedetti,E.; Wright,F.; Lieberman,B.; Ulbricht,B.; Jensik,S.; Myfortic-US01 Renal Transplant Study,GroupClinical transplantation 2007 ;21(2):192-201

Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages.Gao,C.; Guo,H.; Mi,Z.; Grusby,M. J.; Kuo,P. C.Journal of Immunology 2007 ;178(3):1870-1881

Osteopontin regulates ubiquitin-dependent degradation of Stat1 in murine mammary epithelial tumor cells.Gao,C.; Mi,Z.; Guo,H.; Kuo,P. C.Neoplasia (New York) 2007 ;9(9):699-706

Sp1 regulates osteopontin expression in SW480 human colon adenocarcinoma cells.Takami,Y.; Russell,M. B.; Gao,C.; Mi,Z.; Guo,H.; Mantyh,C. R.; Kuo,P. C.Surgery 2007 ;142(2):163-169

Stat1 acetylation inhibits inducible nitric oxide synthase expression in interferon-gamma-treated RAW264.7 murine macrophages.Guo,L.; Guo,H.; Gao,C.; Mi,Z.; Russell,W. B.; Kuo,P. C.Surgery 2007 ;142(2):156-162

One-year results with extended-release tacrolimus/MMF, tacrolimus/MMF and cyclosporine/MMF in de novo kidney transplant recipientsSilva,H. T.,Jr; Yang,H. C.; Abouljoud,M.; Kuo,P. C.; Wisemandle,K.; Bhattacharya,P.; Dhadda,S.; Holman,J.; Fitzsimmons,W.; First,M. R.American Journal of Transplantation 2007 ;7(3):595-608

Little science, big science: strategies for research portfolio selection in academic surgery departments.Shah,A.; Pietrobon,R.; Cook,C.; Sheth,N. P.; Nguyen,L.; Guo,L.; Jacobs,D. O.; Kuo,P. C.Annals of Surgery 2007 ;246(6):1110-1115

Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells.Mi,Z.; Oliver,T.; Guo,H.; Gao,C.; Kuo,P. C.Cancer research 2007 ;67(9):4088-4097

Temporal trends in early clinical outcomes and health care resource utilization for liver transplantation in the United States.Scarborough,J. E.; Pietrobon,R.; Marroquin,C. E.; Tuttle-Newhall,J. E.; Kuo,P. C.; Collins,B. H.; Desai,D. M.; Pappas,T. N.Journal of Gastrointestinal Surgery 2007 ;11(1):82-88

Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation.Palmer,S. M.; Burch,L. H.; Mir,S.; Smith,S. R.; Kuo,P. C.; Herczyk,W. F.; Reinsmoen,N. L.; Schwartz,D. A.Clinical transplantation 2006 ;20(1):30-36

Clinical performance feedback is necessary but not sufficient for longterm success of the academic department of surgery.Kuo,P. C.Journal of the American College of Surgeons 2006 ;203(3):402-403

Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation.Wai,P. Y.; Guo,L.; Gao,C.; Mi,Z.; Guo,H.; Kuo,P. C.Surgery 2006 ;140(2):132-140

Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells.Wai,P. Y.; Mi,Z.; Gao,C.; Guo,H.; Marroquin,C.; Kuo,P. C.Journal of Biological Chemistry 2006 ;281(28):18973-18982

Predictive indices of morbidity and mortality after liver resection.Schroeder,R. A.; Marroquin,C. E.; Bute,B. P.; Khuri,S.; Henderson,W. G.; Kuo,P. C.Annals of Surgery 2006 ;243(3):373-379

Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity.Guo,H.; Gao,C.; Mi,Z.; Wai,P. Y.; Kuo,P. C.Biochemical Journal 2006 ;394(Pt 2):379-387

Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.Mi,Z.; Guo,H.; Wai,P. Y.; Gao,C.; Kuo,P. C.Carcinogenesis 2006 ;27(6):1134-1145

Scheduling the resident 80-hour work week: an operations research algorithm.Day,T. E.; Napoli,J. T.; Kuo,P. C.Current surgery 2006 ;63(2):136-141

Productivity measures associated with a patient access initiative.Gable,W. H.; Pappas,T. N.; Jacobs,D. O.; Cutler,D. A.; Kuo,P. C.Annals of Surgery 2006 ;243(5):604-609

Who should perform liver transplantation? Should that be the transplant surgeon, the hepatobilary surgeon, or the general surgeon? Part I: the transplant surgeon.Desai,D. M.; Kuo,P. C.Journal of Hepatology 2006 ;44(4):647-649

Perioperative management of special populations: immunocompromised host (cancer, HIV, transplantation)Desai,D. M.; Kuo,P. C.Surgical Clinics of North America 2005 ;85(6):1267-1282

Identification of S-nitrosylated proteins in endotoxin-stimulated RAW264.7 murine macrophages.Gao,C.; Guo,H.; Wei,J.; Mi,Z.; Wai,P. Y.; Kuo,P. C.Nitric Oxide 2005 ;12(2):121-126

Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin.Gao,C.; Guo,H.; Mi,Z.; Wai,P. Y.; Kuo,P. C.Journal of Immunology 2005 ;175(1):523-530

Obesity predicts increased overall complications following pancreas transplantation.Hanish,S. I.; Petersen,R. P.; Collins,B. H.; Tuttle-Newhall,J.; Marroquin,C. E.; Kuo,P. C.; Butterly,D. W.; Smith,S. R.; Desai,D. M.Transplantation proceedings 2005 ;37(8):3564-3566

Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells.Guo,H.; Marroquin,C. E.; Wai,P. Y.; Kuo,P. C.Digestive Diseases & Sciences 2005 ;50(7):1288-1298

Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis.Wai,P. Y.; Mi,Z.; Guo,H.; Sarraf-Yazdi,S.; Gao,C.; Wei,J.; Marroquin,C. E.; Clary,B.; Kuo,P. C.Carcinogenesis 2005 ;26(4):741-751

Half-life analysis of pancreas and kidney transplants.Marroquin,C. E.; Edwards,E. B.; Collins,B. H.; Desai,D. M.; Tuttle-Newhall,J. E.; Kuo,P. C.Transplantation 2005 ;80(2):272-275

Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4.Marroquin,C. E.; Wai,P. Y.; Kuo,P. C.; Guo,H.Surgery 2005 ;138(1):93-99

Acute kidney transplant failure following transurethral bladder polyp fulguration.Collins,B. H.; Marroquin,C. E.; Tuttle-Newhall,J. E.; Kuo,P. C.; Preminger,G. M.; Butterly,D. W.Journal of the National Medical Association 2005 ;97(3):414-416

The current status of living donor liver transplantationTuttle-Newhall,J. E.; Collins,B. H.; Desai,D. M.; Kuo,P. C.; Heneghan,M. A.Current problems in surgery 2005 ;42(3):144-183

Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus.Smith,A. D.; Bai,D.; Marroquin,C. E.; Tuttle-Newhall,J. E.; Desai,D. M.; Collins,B. H.; Muir,A.; Kuo,P. C.; McHutchison,J.; Rockey,D. C.Clinical transplantation 2005 ;19(2):250-254

Case 23-2005: a man with a mass in the liver.Smith,A. D.; Morse,M. A.; Kuo,P. C.New England Journal of Medicine 2005 ;353(20):2195-2197

An overview of genomic data analysis.Huang,E. S.; Nevins,J. R.; West,M.; Kuo,P. C.Surgery 2004 ;136(3):497-499

Determining benchmarks for evaluation and management coding in an academic division of general surgery.Kuo,P. C.; Douglas,A. R.; Oleski,D.; Jacobs,D. O.; Schroeder,R. A.Journal of the American College of Surgeons 2004 ;199(1):124-130

Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells.Marroquin,C. E.; Downey,L.; Guo,H.; Kuo,P. C.Immunology letters 2004 ;95(1):109-112

Peroxide-mediated chromatin remodelling of a nuclear factor kappa B site in the mouse inducible nitric oxide synthase promoter.Wei,J.; Guo,H.; Gao,C.; Kuo,P. C.Biochemical Journal 2004 ;377(Pt 3):809-818

The role of Osteopontin in tumor metastasisWai,P. Y.; Kuo,P. C.Journal of Surgical Research 2004 ;121(2):228-241

Intraoperative fluid management during orthotopic liver transplantation.Schroeder,R. A.; Collins,B. H.; Tuttle-Newhall,E.; Robertson,K.; Plotkin,J.; Johnson,L. B.; Kuo,P. C.Journal of Cardiothoracic & Vascular Anesthesia 2004 ;18(4):438-441

A transcriptional repressor of osteopontin expression in the 4T1 murine breast cancer cell line.Gao,C.; Mi,Z.; Guo,H.; Wei,J.; Wai,P. Y.; Kuo,P. C.Biochemical & Biophysical Research Communications 2004 ;321(4):1010-1016

Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior.Mi,Z.; Guo,H.; Wai,P. Y.; Gao,C.; Wei,J.; Kuo,P. C.Journal of Biological Chemistry 2004 ;279(45):46659-46667

S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages.Gao,C.; Guo,H.; Wei,J.; Mi,Z.; Wai,P.; Kuo,P. C.Journal of Biological Chemistry 2004 ;279(12):11236-11243

Liver transplantation from a cadaver donor with ethylene-glycol-induced brain death.Dy-Liacco,M. S.; Tuttle-Newhall,E. J.; Collins,B. H.; Kuo,P. C.Transplantation 2003 ;75(7):1056

Tolerance and the "Holy Grail" of transplantationSchroeder,R. A.; Marroquin,C. E.; Kuo,P. C.Journal of Surgical Research 2003 ;111(1):109-119

Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes.Guo,H.; Wei,J.; Inoue,Y.; Gonzalez,F. J.; Kuo,P. C.American Journal of Physiology - Cell Physiology 2003 ;284(4):1090-1099

Emergencies after liver transplantation.Marroquin,C. E.; Tuttle-Newhall,J. E.; Collins,B. H.; Kuo,P. C.; Schroeder,R. A.Seminars in gastrointestinal disease 2003 ;14(2):101-110

Organ donation and treatment of the multi-organ donorTuttle-Newhall,J. E.; Collins,B. H.; Kuo,P. C.; Schoeder,R.Current problems in surgery 2003 ;40(5):266-310

De-novo cholangiocarcinoma in the setting of recurrent primary sclerosing cholangitis following liver transplant.Heneghan,M. A.; Tuttle-Newhall,J. E.; Suhocki,P. V.; Muir,A. J.; Morse,M.; Bornstein,J. D.; Sylvestre,P. B.; Collins,B.; Kuo,P. C.; Rockey,D. C.American Journal of Transplantation 2003 ;3(5):634-638

Optimization of operating room allocation using linear programming techniques.Kuo,P. C.; Schroeder,R. A.; Mahaffey,S.; Bollinger,R. R.Journal of the American College of Surgeons 2003 ;197(6):889-895

Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells.Gao,C.; Guo,H.; Downey,L.; Marroquin,C.; Wei,J.; Kuo,P. C.Carcinogenesis 2003 ;24(12):1871-1878

Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages.Gao,C.; Guo,H.; Wei,J.; Kuo,P. C.Biochemical & Biophysical Research Communications 2003 ;309(1):120-125

Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection.Rocha,P. N.; Butterly,D. W.; Greenberg,A.; Reddan,D. N.; Tuttle-Newhall,J.; Collins,B. H.; Kuo,P. C.; Reinsmoen,N.; Fields,T.; Howell,D. N.; Smith,S. R.Transplantation 2003 ;75(9):1490-1495

An examination of factors predicting prioritization for liver transplantation.Muir,A. J.; Sanders,L. L.; Heneghan,M. A.; Kuo,P. C.; Wilkinson,W. E.; Provenzale,D.Liver Transplantation 2002 ;8(10):957-961

MR angiography and preoperative evaluation for laparoscopic donor nephrectomy.Jha,R. C.; Korangy,S. J.; Ascher,S. M.; Takahama,J.; Kuo,P. C.; Johnson,L. B.AJR.American Journal of Roentgenology 2002 ;178(6):1489-1495

Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages.Wei,J.; Guo,H.; Kuo,P. C.Journal of Immunology 2002 ;168(9):4721-4727

Pharmacokinetics and biochemical effects of hepapoietin in patients with chronic liver disease.Marino,G.; Rustgi,V. K.; Salzberg,G.; Johnson,L. B.; Kuo,P. C.; Plotkin,J. S.; Flockhart,D. A.Alimentary Pharmacology & Therapeutics 2002 ;16(2):235-242

Surgical techniques in right laparoscopic donor nephrectomy.Buell,J. F.; Hanaway,M. J.; Potter,S. R.; Koffron,A.; Kuo,P. C.; Leventhal,J.; Cho,E.; Johnson,M.; Edye,M.; Woodle,E. S.Journal of the American College of Surgeons 2002 ;195(1):131-137

Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription.Guo,H.; Cai,C. Q.; Kuo,P. C.Journal of Biological Chemistry 2002 ;277(7):5054-5060

Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages.Guo,H. T.; Cai,C. Q.; Schroeder,R. A.; Kuo,P. C.Immunology letters 2002 ;80(1):21-26

Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages.Guo,H.; Cai,C. Q.; Schroeder,R. A.; Kuo,P. C.Journal of Immunology 2001 ;166(2):1079-1086

Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages.Guo,H.; Wei,J.; Kuo,P. C.Biochemical & Biophysical Research Communications 2001 ;289(5):993-997

Are concerns over right laparoscopic donor nephrectomy unwarranted?.Buell,J. F.; Edye,M.; Johnson,M.; Li,C.; Koffron,A.; Cho,E.; Kuo,P.; Johnson,L.; Hanaway,M.; Potter,S. R.; Bruce,D. S.; Cronin,D. C.; Newell,K. A.; Leventhal,J.; Jacobs,S.; Woodle,E. S.; Bartlett,S. T.; Flowers,J. L.Annals of Surgery 2001 ;233(5):645-651

Outcome of extra-anatomic vascular reconstruction in orthotopic liver transplantation.Cappadonna,C. R.; Johnson,L. B.; Lu,A. D.; Kuo,P. C.American Journal of Surgery 2001 ;182(2):147-150

Transplantation of hepatitis C-positive livers in hepatitis C-positive patients is equivalent to transplanting hepatitis C-negative livers.Marroquin,C. E.; Marino,G.; Kuo,P. C.; Plotkin,J. S.; Rustgi,V. K.; Lu,A. D.; Edwards,E.; Taranto,S.; Johnson,L. B.Liver Transplantation 2001 ;7(9):762-768

Dobutamine stress echocardiography for orthotopic liver transplant evaluation.Plotkin,J. S.; Johnson,L. B.; Rustgi,V. K.; Kuo,P. C.; Lu,A. D.Transplantation 2001 ;71(6):818

Candida fasciitis following renal transplantationWai,P. H.; Ewing,C. A.; Johnson,L. B.; Lu,A. D.; Attinger,C.; Kuo,P. C.Transplantation 2001 ;72(3):477-479

Reconsideration of HIV as a contraindication to transplantation.Kuo,P. C.Transplantation 2001 ;71(11):1689

Transplantation in the HIV+ patientKuo,P. C.; Stock,P. G.American Journal of Transplantation 2001 ;1(1):13-17

Expanded criteria donors/high risk recipients is not always cheaper than hemodialysis.Kuo,P. C.; Lu,A. D.; Johnson,L. B.Transplantation 2001 ;72(3):554-555

Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase geneKuo,P. C.; Abe,K.; Schroeder,R. A.Gastroenterology 2000 ;118(3):608-618

Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages.Guo,H. T.; Cai,C. Q.; Kuo,P. C.Biochemical & Biophysical Research Communications 2000 ;277(3):617-621

Medical School
  • Johns Hopkins University School of Medicine
  • Brigham and Women's Hospital, General Surgery
  • Beth Israel Deaconess Medical Center/Harvard University Medical School, Transplant/Hepatobiliary Surgery