NCT00898079

Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

Study Contact:

Study Phase:

Recruitment Status:

COMPLETED

NCT ID:

NCT00898079

Principal Investigator:

Study Type:

OBSERVATIONAL

Official Title:

A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

Summary

This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.

Eligibility

Inclusion Criteria:

* Meets any of the following criteria:

* Diagnosed with primary neoplasm
* Developed a second malignant neoplasm
* Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in the International Classification of Disease for Oncology, Third Edition
* Must have biological specimens including solid tumors and leukemias available

* Solid tumors meeting the following criteria:

* Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed (block or tissue in formalin) primary tumor AND at least 10 unstained paraffin slides for NIH Mandated QC (tumors that have undergone central pathology review are allowed)

* Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
* Pleural fluid or cytologic specimens meeting the following criteria:

* At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2 unstained smears)

* Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
* ALL/AML

* 3-6 mL of bone marrow aspirate and 10 mL of whole blood
* Not eligible for disease-specific biology or banking protocol

Disease(s) and\or Condition(s)

Acute Undifferentiated Leukemia

Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

Childhood Acute Lymphoblastic Leukemia

Childhood Acute Myeloid Leukemia

Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive

Childhood Solid Neoplasm

Chronic Lymphocytic Leukemia

Hairy Cell Leukemia

Juvenile Myelomonocytic Leukemia

Mast Cell Leukemia

Neoplasm of Uncertain Malignant Potential

Prolymphocytic Leukemia

Secondary Acute Myeloid Leukemia

T-Cell Large Granular Lymphocyte Leukemia

Primary Purpose

Intervention/Treatment

- Type: OTHER
- Name: Cytology Specimen Collection Procedure
- Description: Correlative studies
- Arm Group Labels: Observational

Sponsor

Children's Oncology Group