NCT03378765

Gut Microbiota, Short Chain Fatty Acids, and Adiposity Across The Epidemiological Transition

Official Title:

Gut Microbiota, Short Chain Fatty Acids, and Adiposity Across The Epidemiological Transition

Summary

The objective of this study is to define associations between gut microbiota, SCFAs and obesity in populations spanning the epidemiologic transition, and explore mechanisms by which these factors may independently and collectively influence the development of obesity. The central hypothesis of this study is that the composition of gut microbiota drives SCFA production which in turn influences obesity risk at the population-level.

Eligibility

Inclusion Criteria:

* Identify as African American or Black
* Age 18-50

Exclusion Criteria:

* Pregnancy, nursing, or planning to become pregnant
* Movement disorders or other disability that limits mobility

Disease(s) and\or Condition(s)

Obesity

Diabetes

Primary Purpose
Intervention/Treatment
    • Type: BEHAVIORAL
    • Name: Diet and physical activity monitoring
    • Description: Lifestyle monitoring
    • Arm Group Labels: African origin adults
Sponsor
  • Loyola University