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Nina Clark, MD

Nina Clark.

Dr. Clark is the Director of the Infectious Diseases Division and interim Co-Director of Loyola University Stritch School of Medicine’s Infectious Disease and Immunology Research Institute.  She trained in Internal Medicine and Infectious Diseases at the University of Michigan where she did basic science research in retroviral infections and was active in the UM HIV program.  She directs the Transplant Infectious Diseases Program at Loyola and oversees Loyola’s Ryan White grant from the Health Resources and Services Administration which provides resources for the care of persons with HIV/AIDS.  Her current research efforts include multicenter trials of novel antimicrobials and investigator-initiated studies of infections in transplant recipients. 


  1. Grim, S.A., Pham, T., Thielke, J., Sankary, H., Oberholzer, J., Benedetti, E., and Clark, N.M.  Infectious complications associated with the use of rituximab for ABO-incompatible and positive cross-match renal transplant recipients.  Clinical Transplantation, 21:628-32, 2007.
  2. Reid, G.E., Grim, S.A., Sankary, H., Benedetti, E., Oberholzer, J. and Clark, N.M.  Early intraabdominal infections associated with orthotopic liver transplantation. Transplantation, 87(11):1706-11, 2009.
  3. Sun, H-Y., Aguado, J.M., Bonatti, H., Forrest, G., Gupta, K.L., Safdar, N., John, G.T., Pursell, K.J., Munoz, P., Patel, R., Fortun, J., Martin-Davila, P., Philippe, B., Philit, F., Tabah, A., Terzi, N., Chatelet, V., Kusne, S., Clark, N., Blumberg, E., Marino Blanes, J., Humar, A., Houston, S., Lass-Florl, C., Johnson, L., Dubberke, E.R., Barron, M.A., Lortholary, O. and Singh, N.  Pulmonary zygomycosis in solid organ transplant recipients in the current era.  Am J Transplant, 9(9):2166-71, 2009.
  4. Grim, S.A., Pereira, E., Guzman, G., and Clark, N.M.  CMV PCR as a diagnostic tool for CMV gastrointestinal disease after solid organ transplantation.  Transplantation, 90(7):799-801, 2010.
  5. Grim, S.A. and Clark, N.M.  Management of infectious complications in solid-organ transplant recipients.  Clinical Pharmacology and Therapeutics 90(2):333-42, 2011.
  6. Grim, S.A., Proia, L., Miller, R., Alhyraba, M., Costas-Chavarri, A., Oberholzer, J. and Clark, N.M.  A multicenter study of histoplasmosis and blastomycosis after solid organ transplantation. Transplant Infectious Diseases 14(1):17-23, 2012.
  7. Grim, S.A., Berger, K., Teng, C., Gupta, S., Layden, J.E., Janda, W.M., and Clark, N.M.  Timing of susceptibility-based antifungal drug administration in patients with Candida bloodstream infection:  correlation with outcomes.  Journal of Antimicrobial Chemotherapy 67(3):707-14, 2012.
  8. Layden, J., Cotler, S., Brown, K., Lucy, M., Te, Helen, Eswaran, S., Fimmel, C., Layden, T. and Clark, N.  Racial differences in fibrosis progression after HCV-related liver transplantation.  Transplantation, 94(2):178-84, 2012.
  9. Clark, N.M., Lynch J.P., Sayah, D., Belperio, J.A., Fishbein, M.C. and Weigt, S.  DNA viral infections complicating lung transplantation.  Seminars in Respiratory and Critical Care Medicine, 34:380-404, 2013.
  10. Reid G,  Grim S, Campara M, Tang I, Clark N.  “Use of Fosfomycin for MDR UTIs in Kidney Transplant Recipients.” Transplantation Aug 2013 96(3): 312-14. 
  11. Cannon, J.P., Lee, T.A., Clark, N.M., Setlak, P., and Grim, S.A.? The risk of seizures among the carbapenems: a meta-analysis. Journal of Antimicrobial Chemotherapy, 69(8):2043-55, 2014.
  12. Grim, S.A., Layden, J.E., Jain, P., Gallitano, S., Adams, W., and Clark, N.M.  Latent tuberculosis in abdominal transplant patients:  a review of treatment practices and outcomes.  Transplant Infectious Diseases 17(5):768-77, 2015.
  13. Clark, N.M., Grim, S.A., and Lynch, J.P.  Posaconazole:  use in the prophylaxis and treatment of fungal infections.  Seminars in Respiratory and Critical Care Medicine 36:776-94, 2015.
  14. Roth, P., Grim, S., Gallitano, S., Clark, N., and Layden, J.  Serial testing for latent tuberculosis infection in transplant candidates:  a retrospective review.  Transplant Infectious Diseases 18:14-21, 2016.
  15. G., Lawrence, S.J., Theodoropoulos, N., Clark, N.M., Razonable, R.R., Alangaden, G., Miller, R., Smith, J., Young, J.A., Hawkinson, D., Pursell, K. and Kaul, D.R.  Current practices for treatment of respiratory syncytial virus and other non-influenza respiratory viruses in high-risk patient populations:  a survey of institutions in the Midwestern Respiratory Virus Collaborative.  Transplant Infectious Diseases 18(2):210-5, 2106.
  16. Seroy, J.T., Grim, S.A., Reid, G.E., Wellington, T., and Clark, N.M.  Treatment of multidrug-resistant urinary tract infections with oral fosfomycin, a retrospective analysis.  Journal of Antimicrobial Chemotherapy 71(9):2563-8, 2016.
  17. Reid, G.E., Lynch, J.P., Weigt, S., Sayah, D., Belperio, J.A., and Clark, N.M.  Herpesvirus respiratory infections in immunocompromised patients:  epidemiology, management and outcomes.  Seminars in Respiratory and Critical Care Medicine 37(4):603-30, 2016.
  18. Grim, S.A., Reid, G.E., and Clark, N.M.  Update in the treatment of non-influenza respiratory virus infection in solid organ transplant recipients.  Expert Opinion on Pharmacotherapy 18(8):767-79, 2017.
  19. Seroy, J., Antiporta, A., Grim, S.A., Proia, L.A., Singh, K., and Clark, N.M.  Aspergillus calidoustus case series and review of the literature.  Transplant Infectious Diseases 19(5):e12755, 2017.
  20. Clark, N.M., Weigt, S.S., Fishbein, M.C., Kubak, B., Belperio, J.A., Lynch, J.P.  Fungal infections complicating lung transplantation.  Seminars in Respiratory and Critical Care Medicine 39:227-54, 2018.
  21. Clark, N.M.  Skin and soft tissue infections.  In Textbook of Diagnostic Microbiology, Ed. Connie Mahon, Donald Lehman, and George Manuselis, Elsevier, Philadelphia, PA, 6th edition, 2018 Chapter 33, pp.795-828.
  22. Restrepo, A. and Clark, N.M. Nocardia infections in solid organ transplantation:  Guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation.  Clinical Transplantation 2019 33(9):e13509.
  23. Clark, N.M. and Cotler, S.J.  Infectious complications in liver transplantation.  In UpToDate, Ed. T.W. Post, UpToDate, Waltham, MA, last update April 2020.
  24. Wenzler, E., Santarossa, M., Meyer, K.A., Harrington, A.T., Reid, G.E., Clark, N.M., Albarillo, F.S., Bulman, Z.P.  In vitro pharmacodynamic analyses help guide the treatment of multidrug-resistant Enterococcus faecium and carbapenem-resistant Enterobacter cloacae complex bacteremia in a liver transplant patient.  Open Forum Infectious Diseases, epub 1/4/20;
  25. Lynch, J.P., Reid, G, Clark, N.M.  Nocardia spp: a rare cause of pneumonia globally.  Seminars in Respiratory and Critical Care Medicine 41:538-54, 2020.