Ex Vivo Lung Perfusion (EVLP)


Clinical Trial to Increase Suitability of Donor Lungs for Transplantation

Loyola Medicine was one of six sites in the United States that participated in a clinical trial for ex vivo lung perfusion (EVLP). This technology improves the function of the donor lung and allows for a more accurate assessment of organ suitability. Through participation in this clinical trial, Loyola made lung transplantation available to more patients than was previously possible.

EVLP is a modern preservation technique that allows for the use of donor lungs that might have previously been unsuitable for transplantation. The ex vivo lung perfusion machine uses an ICU ventilator to inflate and deflate the donor lungs, and a machine to circulate blood substitute through the lungs.

Loyola’s lung transplant surgeons evaluate the suitability of the donor lung with the intended recipient in mind. After undergoing EVLP, the donor organ may or may not be determined to be suitable for transplant.

Lung transplant surgery is the only life-saving treatment option for many patients with end-stage lung disease. Suitability of the donor organ is of the utmost importance for the success of the surgery and the patient’s future health.

Through ex vivo lung perfusion, Loyola’s transplant surgeons are bringing life-saving treatment to more patients who need lung transplants.

Doctor with patient

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