NCT00007007

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Official Title:

A Feasibility Study of Neurocognitive Evaluation in Patients Treated for Brain Metastases

Summary

RATIONALE: Assessment of patients undergoing radiation therapy may help to determine the effects of the treatment and may help improve cancer treatment.

PURPOSE: This clinical trial is studying the memory skills in patients receiving radiation therapy for brain metastases.

Eligibility

DISEASE CHARACTERISTICS: Histologically proven primary malignancy No primary site of hematopoietic origin (leukemia) No leptomeningeal involvement At least 1 measurable brain metastasis by CT or MRI

PATIENT CHARACTERISTICS: Age: Not specified Performance status: Zubrod 0-1 Life expectancy: At least 3 months Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: Not pregnant or nursing Fertile patients must use effective contraception Neurological function classification 0-2 No major medical illnesses or psychiatric impairments that would preclude study

PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: Not specified Endocrine therapy: Not specified Radiotherapy: No prior radiotherapy to the brain Surgery: Not specified

Disease(s) and\or Condition(s)

Cognitive/Functional Effects

Metastatic Cancer

Radiation Toxicity

Primary Purpose
  • OTHER
Intervention/Treatment
    • Type: PROCEDURE
    • Name: management of therapy complications
    • Description:
    • Arm Group Labels: Whole brain radiation therapy + neurocognitive assessments
    • Type: PROCEDURE
    • Name: quality-of-life assessment
    • Description:
    • Arm Group Labels: Whole brain radiation therapy + neurocognitive assessments
Sponsor
  • Radiation Therapy Oncology Group