NCT00466804
Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients
COMPLETED
NCT00466804
OBSERVATIONAL
Observational Study of Alloimmunity in Cardiac Transplant Recipients
Injury of transplant tissue by a transplant recipient's immune system continues to be the leading cause of graft rejection and recipient death. The purpose of this study is to identify a single test or a combination of noninvasive tests currently used for heart transplant monitoring that correlate to long-term graft survival.
Inclusion Criteria:
* Age greater than 10 and a body mass of 30 kg (66 lbs) or more
* On waiting list for a heart transplant for whom a donor heart available
* Willing to comply with study protocol
* Willing to use acceptable forms of contraception
* Parent or guardian willing to provide consent, if applicable
Exclusion Criteria:
* Receiving multiple organ transplants
* Previously received organ transplants
* Other comorbidities that, in the opinion of the site investigator, would interfere with the study
* Currently taking immunosuppression for nontransplant reasons
* Participation in an interventional clinical trial
* Pregnancy or breastfeeding
Heart Transplant
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- Type: PROCEDURE
- Name: Heart transplant
- Description: People in this study will have a heart transplant and be monitored for signs of rejection
- Arm Group Labels: Heart Transplant Recipients
- National Institute of Allergy and Infectious Diseases (NIAID)