NCT03878290
RiSE to Prevent Cardiovascular Disease in African Americans
NA
COMPLETED
NCT03878290
INTERVENTIONAL
RiSE to Prevent Cardiovascular Disease in African Americans
The purpose of this pilot study is to evaluate an innovative 8-wk stress reduction program called Resilience, Stress and Ethnicity (RiSE) program designed to reduce chronic stress associated with perceived discrimination among African Americans. African Americans residing in the Maywood community between the ages of 25 and 75 with at least one cardiovascular disease risk factor such as being overweight, having high blood pressure, or diabetes will be enrolled. The following specific aims will be addressed:
Aim 1: Determine the feasibility and acceptability of the program as a strategy to reduce chronic stress in African Americans within the Maywood and surrounding community.
Aim 2: Examine the extent to which training in RiSE (1) improves psychological well being, (2) decreases inflammatory burden, and (3) reduces cardiovascular risk in African Americans
Participants will be randomized to either the RiSE program or the control (no intervention group). Participants will provide blood and saliva samples as well as complete written questionnaires asking them questions about their health, well-being, and early life at the start of the study, half way through the study (at 4 weeks), at the completion of the intervention (8 weeks) and 3 months after the completion of the intervention).
Inclusion Criteria:
* African American
* Living in Maywood community or surrounding area
* Able to speak, read, write English
* Have at least one of the following:
* Body Mass Index (BMI) \> 25 (overweight or obese)
* Total cholesterol \> 240
* Diabetes mellitus
* Systolic blood pressure the same or greater than 120 mmHg or diagnosis of hypertension and/or taking antihypertensive medication
* Atrial fibrillation
* Parental history of myocardial infarction (MI) (heart attack) prior to age 60
Exclusion Criteria:
* Current smoker (smoked in last month)
* History of myocardial infarction or ischemic heart disease
* Current cancer
* Active infection
* Major Immune-related disorder (lupus,MS)
* Substance abuse
* Immune-altering drugs
* Recent dental procedure (within past 72 hours
* Bleeding gums or periodontal disease
Atherosclerosis
Stress
Hypertension
Dyslipidemias
Obesity
Diabetes
Coronary Artery Disease
- PREVENTION
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- Type: BEHAVIORAL
- Name: Resilience, Stress, and Ethnicity (RiSE)
- Description: Group based stress reduction program focused on helping minorities develop coping and empowerment skills
- Arm Group Labels: 8-week RiSE
- Loyola University