MacNeal Hospital Launches First Clinical PROACTIVE-HF Trial in Illinois for Congestive Heart Failure Patients
June 25, 2020Categories: MacNeal Hospital, Heart & Vascular
Tags: Heart Vascular, MacNeal Hospital
BERWYN, IL – MacNeal Hospital is the first hospital in Illinois to participate in a national, randomized clinical trial using daily vital signs and lung pressure measurement to manage patients with congestive heart failure (CHF). The PROACTIVE-HF trial utilizes a new monitoring system, coupled with a pressure sensor, implanted directly into a blood vessel in the lung. This system provides information that is recorded and transmitted over a cellular or Wi-Fi connection to a patient’s provider, allowing for medication changes, if necessary, to prevent further health deterioration or hospitalization.
Cardiologists Gregory Macaluso, MD, and James Sur, MD, performed the first implant of the new Cordella Heart Failure System in Illinois (the fourth in the U.S.) at MacNeal’s recently renovated, state-of-the-art Cardiac Catherization Lab. MacNeal Hospital is part of Loyola Medicine.
“The increase in lung pressure is the earliest signal that the heart is straining or decompensating,” said Dr. Macaluso of Heart Care Centers of Illinois. “This device can detect changes in a patient’s heart before most symptoms can occur.”
The sensor is implanted into a lung blood vessel using a common outpatient cardiac procedure. Lung pressures are then recorded daily and transmitted via a small hand-held reader to a secure website that is accessible to providers. In addition, providers may be alerted if pressures fall outside of a pre-specified range.
“This allows more proactive, closer monitoring of the patient and an opportunity to fine-tune helpful, guideline-directed medication,” said Dr. Macaluso. “Ultimately, it reduces
the likelihood of admission to the hospital, which can be associated with worse health outcomes.”
Additionally, the device is coupled with a monitoring system that measures blood pressure, weight, oxygen levels and symptoms, providing a comprehensive overview of a patient’s health. Most importantly, patients do not need to leave their home to transmit this health data.
“This is a huge benefit as we move into the future of remote monitoring of patients and in light of the COVID-19 pandemic,” said Dr. Macaluso. Cardiovascular disease is the leading cause of death in the United Sates and patients diagnosed with cardiovascular disease are at higher risk for severe COVID-19 complications.
“As one of the region’s top cardiovascular hospitals, MacNeal is pleased to participate in this innovative clinical trial that has the potential to substantially improve care and treatment for patients living with heart disease,” said Charles J. Bareis, MD, chief medical officer at MacNeal. MacNeal was recently named to the 2020 IBM Watson Health® 50 Top Cardiovascular Hospitals list for the second consecutive year.
A total of 1,000 patients are expected to participate this national clinical trial. The Cordella Heart Failure System is manufactured by Endotronix in Lisle, Illinois. For more information on the Cordella Heart Failure System clinical trial, please contact MacNeal Hospital at 708-783-3305.
About Loyola Medicine
Loyola Medicine, a member of Trinity Health, is a nationally ranked academic, quaternary care system based in Chicago's western suburbs. The three-hospital system includes Loyola University Medical Center (LUMC), Gottlieb Memorial Hospital, MacNeal Hospital, as well as convenient locations offering primary care, specialty care and immediate care services from nearly 2,000 physicians throughout Cook, Will and DuPage counties. LUMC is a 547-licensed-bed hospital in Maywood that includes the William G. and Mary A. Ryan Center for Heart & Vascular Medicine, the Cardinal Bernardin Cancer Center, the John L. Keeley, MD, Emergency Department, a Level 1 trauma center, Illinois's largest burn center, the Nancy W. Knowles Orthopaedic Institute, a certified comprehensive stroke center, transplant center and a children’s hospital. Having delivered compassionate care for over 50 years, Loyola also trains the next generation of caregivers through its academic affiliation with Loyola University Chicago’s Stritch School of Medicine and Marcella Niehoff School of Nursing.
For more information, visit loyolamedicine.org. You can also follow Loyola Medicine on LinkedIn, Facebook, Instagram or X (formerly known as Twitter).
About Trinity Health
Trinity Health is one of the largest not-for-profit, faith-based health care systems in the nation. It is a family of 127,000 colleagues and more than 38,300 physicians and clinicians caring for diverse communities across 26 states. Nationally recognized for care and experience, the Trinity Health system includes 93 hospitals, 107 continuing care locations, the second largest PACE program in the country, 142 urgent care locations and many other health and well-being services. In fiscal year 2024, the Livonia, Michigan-based health system invested $1.3 billion in its communities in the form of charity care and other community benefit programs. For more information, visit us at www.trinity-health.org, or follow us on LinkedIn, Facebook, and X (formerly known as Twitter).